Figure 1. Representation of process of generating brain organoids. PSCs isolated from iPSCs or ESCs, differentiate into an embryoid body. The differentiating PSCs organize themselves into a structure called neuroectoderm that subsequently matures into an organoid.
Figure 2. Schematic flow chart illustrating the diverse applications and potential of organoid intelligence in the realm of neuroscience and medical research.
Figure 3. Timeline for the development of biocomputers. A summary of key landmark studies leading to the fundamental understanding of biocomputers.
Figure 4. Schematic representation of the development process of OI. The process starts with PSCs and progresses through differentiation into neural progenitor cells, self-organization into brain organoids, AI analysis of organoid activities, optimization of organoid production with AI, integration with biologically relevant scaffolds like B-ECM hydrogels, and culminates in the creation of ‘intelligence-in-a-dish’.